- City of Charleston Collection113
- Burton L. Padoll Papers, 1957-2009110
- Photograph Survey of the “Charleston Center” Site110
- Temple Sinai (Sumter, S.C.) Records106
- City of Charleston Board of Architectural Review Photographs Collection105
- MUSC College of Nursing Class Photos105
- James Glen Papers102
- George LaGrange Cook Photograph Collection99
- Agricultural Society of South Carolina Visual Materials98
- Personal Photographs of Sergeant Jesse Herring, Jr. during WWII, Fort Moultrie, South Carolina95
- Rabbi Jacob S. Raisin Papers87
- Mamie E. Garvin Fields Papers, 1894 - 198786
- Stereographic Views of South Carolina86
- Minutes of the Annual Conferences of the Baptist, Episcopal, Lutheran, Methodist, and Presbyterian Churches in South Carolina, 1785-192083
- Edmondston-Alston Family Letters and Paper Materials, 1782-191982
- Diaries80
- Medical Society of South Carolina Digital Collections80
- Waring Historical Library Medical Caricatures80
- George W. Williams Photograph Collection77
- Georgetown County Digital Library77