Collection
- Roslin Plantation Journal, 1813-18151
- Russell Maxey Photograph Collection10
- SCDOT Photographs: Properties in the Right-of-Way22
- Samuel Lander Papers1
- Sargeant Studios1
- Scenes in Charleston, ca. 1940s1
- Schools of Greenville County1
- Senator Burnet R. Maybank Papers, 1914-19731
- Septima P. Clark Papers, ca. 1910-ca. 19906
- Sheet music from the Joseph M. Bruccoli Great War Collection4
- Simons & Lapham Architectural Drawings, 1919-195214
- Singing the Archives1
- Skateboarding's Journey to the Olympics Oral History Collection2
- Slave Records in the Discrete Manuscript Collection5
- South Carolina Aerial Photograph Indexes, 1937-19897
- South Carolina Baptist Church Records1
- South Carolina Department of Transportation County Road Maps11
- South Carolina Fall Line Collection3
- South Carolina Historical Records Survey Collection4
- South Carolina Hospital Postcards1