- Georgetown County Memories1
- Gertrude Sanford Legendre Papers, 1844-199616
- Government Information Pamphlet Collection2
- Greenville Downtown Campus (1851-1958)2
- Grimke family papers, 1678-19775
- Gussie Johnson Papers, 1940-20001
- Hampstead and Bethany Cemeteries1
- Harry and William Birch Collection4
- Harvey Gantt and the Integration of Clemson University62
- Henrietta Yurchenco Field Recordings, 1970-19711
- Henry William Ravenel Papers, 1739-19354
- Henry William Ravenel, Plants and Planter74
- Heyward and Ferguson Family Papers, 1806-19234
- Historic Southern Naturalists11
- Historical and Governing Records, 1841-19253
- In Camp And At The Front, WW1 Selections, South Carolina Political Collections2
- Irish Heritage Oral History Collection1
- Isaiah Bennett Papers, ca. 1932-20025
- J. Arthur Brown Papers, 1937 - 19881
- James Glen Papers1