Collection
- Ball Family Papers, 1631-18962
- Barnwell Family Papers3
- Beaty Family Scrapbook2
- Belle W. Baruch Collection35
- Berkeley County (S.C.) Memories8
- Berkeley County Photograph Collection3
- Bookmobiles1
- Books and Pamphlets1
- Bratton Family Papers, 1764-19836
- Bratton Family Papers, 1764-1983.3
- Businesses of Greenville County3
- C. Wayne Weart Pharmacy History Collection1
- Carl Julien Collection13
- Carlton Simmons Collection2
- Carolina Textile Mills2
- Catherine and James Yatsco Collection1
- Charles N. Bayless Photos of Charleston and Georgetown County, S.C.10
- Charleston Branch of the National Association for the Advancement of Colored People Papers, 1920-19956
- Charleston Museum Collection of Revolutionary War Letters1
- Charleston Museum Earthquake Photographs1