- Stereoscopic Photographs2
- Stokes Grocery Store Ledger2
- The Charleston Oral History Program2
- William A. Rosenthall Judaica Collection - Prints and Photographs2
- Williams, Chesnut, Manning Family Papers, 1682-19262
- Agricultural Society of South Carolina Visual Materials1
- Augusta Baker Papers, 1911-19981
- Barnwell Family Papers1
- Belle W. Baruch Collection1
- Certificate of citizenship, 1871 - McCormick, John, fl. 18711
- City Engineers's Plat Book, 1671-19511
- Collected Papers of the Holland Family of Greenville County1
- Fairfield County Manuscript Collection1
- Forgotten Books1
- Georgetown County Historical Survey1
- Georgetown County Library Collection1
- Home Movies from Moving Image Research Collections1
- Jeffersonian Americana1
- John F. Riley papers, 1884-1921 (bulk 1884-1895)1
- Journal of Charles Cotesworth Pinckney's plantations, 1818-18191