- Charles N. Bayless Photos of Charleston and Georgetown County, S.C.9
- Furman University Historical Images9
- Greenville Downtown Campus (1851-1958)8
- Columbia Theater and Entertainment7
- Black and white negatives of South Carolina State Parks, 1934-19676
- Civil Rights Films from Moving Image Research Collections6
- Henry William Ravenel, Plants and Planter6
- White Pines Series of Architectural Monographs Collection6
- John Henry McCray papers, 1929-19895
- The Joel Myerson Collection of Nineteenth-Century American Manuscripts, Images, and Ephemera5
- Augusta Baker Papers, 1911-19984
- Nathaniel Russell Middleton Papers, 1823-18814
- SCDOT Photographs: Properties in the Right-of-Way4
- Senator Burnet R. Maybank Papers, 1914-19734
- Williams Furniture Company Collection4
- YWCA of Greater Charleston, Inc., Records, 1906 - 20074
- Butler Derrick: In His Own Words3
- Edwin Hughes Collection3
- Pawleys Island Civic Association3
- Robert McNair: In His Own Words3