Collection
- Clemson University Historical Images2
- Colin J. McRae Papers, Huse Audit Series1
- Colleton County Memorial Library Map Collection1
- Color Slides from Fort Sumter National Historical Monument55
- Color Slides of Congaree National Park33
- Color slides of South Carolina State Parks30
- Communities - Berea1
- Communities - Simpsonville5
- David Wyatt Aiken Papers, 1849-19761
- Diamond Fields of South Africa: Memoirs, Mines, and Minerals7
- Digital Collection (Relation)1
- Documentation for the People: Celebrating 125 Years as a Federal Depository Library14
- Edmondston-Alston Family Letters and Paper Materials, 1782-191910
- Episcopal Church of the Advent1
- Equality of Educational Opportunity by James S. Coleman10
- Fairfield Plantation Papers2
- Family Bible Records1
- Forgotten Books1
- Fox Movietone News Collection38
- From the Kitchen Drawer and Cupboard: The Jerred Metz Collection of Manufacturers' Recipe and Advertisement Booklets 1902-19502