- Proclamations, Politics, and Commerce: Broadsides from the Colonial Era to the Present at the South Caroliniana Library45
- Alexander McBeth Store Ledger, 179444
- Sheet music from the Joseph M. Bruccoli Great War Collection44
- University of South Carolina Student Exams, 1854 - 191743
- Joseph A. DeLaine Papers42
- SCDOT Photographs: Properties in the Right-of-Way40
- William A. Rosenthall Judaica Collection - Prints and Photographs38
- South Caroliniana Library Map Collection37
- The Joel Myerson Collection of Nineteenth-Century American Manuscripts, Images, and Ephemera37
- South Carolina Historical Records Survey Collection36
- Civil War Pamphlets35
- Berkeley County (S.C.) Memories34
- Bratton Family Papers, 1764-198332
- Photographic Record of the Cooper River Bridge30
- South Carolina State Parks Signs, Brochures, and Manuals30
- Barnwell Family Papers28
- Civil Rights Films from Moving Image Research Collections28
- Fairfield County Manuscript Collection28
- Augusta Baker Papers, 1911-199827
- Drayton Family Papers, 1837-186927