Collection
- Greenville South Carolina Newspapers1
- Grimke family papers, 1678-19771
- HCAC Research1
- Historical Newspapers1
- Irish Heritage Oral History Collection1
- Isaiah DeQuincey Newman Papers1
- John Shaw Billings Scrapbook1
- Joseph A. DeLaine Papers1
- Oliver Hart papers, 1741-19611
- Postcards of the Midlands1
- Senator Burnet R. Maybank Papers, 1914-19731
- Sidney and Lanny Palmer Collection1
- Slater Mill1
- South Carolina Children's Library Services Collection1
- South Carolina Historical Society Oral Histories1
- South Carolina and the Civil War1
- The American Revolution in South Carolina1
- Tom Crosby oral history collection, 2006-20111
- Town of Sullivan's Island Historic Meeting Minutes1
- Voices of the Santee Delta Oral History Project1