Collection
- C. Wayne Weart Apothecary Trade Cards, 1870-19204
- Call for Change1
- Camilla Urso Collection2
- Camp Sevier 1
- Carl Julien Collection15
- Carolina Bands Collection1
- Carolina Textile Mills9
- Catherine M. McCottry, M.D. Papers1
- Cemeteries1
- Center for Women's and Gender Studies 20th Anniversary Poster Collection7
- Certificate of citizenship, 1871 - McCormick, John, fl. 18711
- Charles Fraser Book of Precedents, 1800-18191
- Charles Fraser's Sketchbook, 1796-18053
- Charles N. Bayless Photos of Charleston and Georgetown County, S.C.99
- Charleston Branch of the National Association for the Advancement of Colored People Papers, 1920-199570
- Charleston City Directories3
- Charleston Earthquake 188627
- Charleston Museum Collection of Revolutionary War Letters18
- Charleston Museum Earthquake Photographs4
- Charleston Museum Illustrated Newspapers Collection21