Collection
- David Wyatt Aiken Papers, 1849-19761
- Dientje Krant Kalisky Adkins Photographs, 1938-19961
- Documenting the African American Experience at Clemson15
- Downtown Greenville3
- Drayton Papers, 1701-20041
- Due West Female College Photograph Collection1
- E. Don Herd Photograph Collection4
- Edmondston-Alston Family Letters and Paper Materials, 1782-19195
- Edwin A. Harleston Collection1
- Edwin Hughes Collection10
- Eleanor Parsons Moody Collection4
- Election 2020 Oral History Collection4
- Equal Rights Amendment56
- Erastus W. Everson Papers, 1837-18931
- Erskine College Photograph Collection2
- Fairfield County Manuscript Collection2
- Family Bible Records2
- Forgotten Books7
- Fox Movietone News Collection229
- Fritz Hollings: In His Own Words20