Collection
- Strom Thurmond Collection, Mss 10043
- University of South Carolina Film and Video Collections43
- University of South Carolina Student Exams, 1854 - 191743
- Edmondston-Alston Family Letters and Paper Materials, 1782-191942
- Eleanor Parsons Moody Collection42
- History of the University of South Carolina School of Medicine - Columbia42
- Hunger in America42
- Barnwell Family Papers41
- Henry Laurens papers, 1747-186040
- Russell Maxey Photograph Collection40
- Herald-Journal Willis Collection38
- Panoramic Photographs Collection36
- Colin J. McRae Papers, Huse Audit Series35
- Belle W. Baruch Collection34
- William ("Bill") Saunders Papers, circa 1950 - 200433
- Works Progress Administration photograph collection: South Carolina places : 193u-194u.32
- Joseph A. DeLaine Papers31
- Thomas J. Blumer Collection on the Catawba Nation, 1756 - Present31
- Andrews Museum Collection30
- Georgetown County Library Collection30