Collection
- Columbia Theater and Entertainment1
- Communities - Fountain Inn1
- Communities - Simpsonville2
- Continental Army Southern Department Records, 1778-1890 (Bulk 1778-1780)22
- Cooperative Annual Reports7
- Cote Bas and Mepkin Plantations Journals, 1865-18772
- Course Catalogs1
- David Wyatt Aiken Papers, 1849-19769
- Delbert Claire Brandt Collection24
- Diaries106
- Downtown Greenville13
- Drayton Family Papers, 1837-18692
- Drayton Papers, 1701-20044
- E. Don Herd Photograph Collection5
- E.T. Start Photograph Collection4
- Edisto Island Historic Preservation Society Oral Histories2
- Edmondston-Alston Family Letters and Paper Materials, 1782-19199
- Edwin Hughes Collection394
- Eleanor Parsons Moody Collection8
- Election 2020 Oral History Collection3