Collection
- Edwin Hughes Collection15
- Eighteenth & Nineteenth Century Correspondence Collection3
- Eleanor Parsons Moody Collection42
- Elizabeth Pringle Diaries47
- Emily Clarkson Ball Grainger Family Papers, 1839-1962 (bulk 1926-1950)1
- Episcopal Church of the Advent2
- Equal Rights Amendment17
- Erastus W. Everson Papers, 1837-18932
- Eric Crawford Spiritual Recordings, 2007-20101
- Erskine College Photograph Collection4
- Esau Jenkins Papers, 1963-200320
- Ethelyn Murray Parker Papers1
- Eugene C. Hunt Papers, 1834 - 199412
- Fairfield County Manuscript Collection28
- Fairfield High School Oral History Collection3
- Family Bible Records17
- Flagg Family Papers, 1832-192617
- Forgotten Books20
- Fort Jackson Library Collection2
- Fox Movietone News Collection484