Collection
- Robert F. W. Allston papers, 1817-18681
- Ron Swain Map Collection1
- Rural Heritage Lexington County Exhibit photographed by Richard Taylor1
- Russell Maxey Photograph Collection3
- SCDOT Photographs: Properties in the Right-of-Way24
- Sanborn Fire Insurance Maps of South Carolina1
- Senator Burnet R. Maybank Papers, 1914-19731
- Septima P. Clark Papers, ca. 1910-ca. 19902
- Shakespeare First Folio Teaching Resources1
- Sheet music from the Joseph M. Bruccoli Great War Collection2
- South Carolina Aerial Photograph Indexes, 1937-19898
- South Carolina Baptist Church Records1
- South Carolina Department of Transportation County Road Maps15
- South Carolina Historical Records Survey Collection19
- South Carolina Hospital Postcards1
- South Carolina Postcards22
- South Carolina State Parks Signs, Brochures, and Manuals46
- South Carolina Veterans Oral History Collection1
- South Carolina and World War II6
- South Carolina and the Civil War5