- Phosphates in South Carolina, 1870-18903
- Photographic Record of the Cooper River Bridge2
- Photos from the Records of The Historic Preservation Planner, BCD-COG35
- Piedmont Image Collection1
- Piedmont Manufacturing1
- Political Campaign Memorabilia Collection2
- Postcard Collection of Mullins, South Carolina2
- Primary Sources for K-12, Pilot Project2
- Proclamations, Politics, and Commerce: Broadsides from the Colonial Era to the Present at the South Caroliniana Library2
- Residences2
- Richard Furman and James C. Furman Collection1
- Richard L. Walker: In His Own Words1
- Richmond Plantation Journal, 1859-18601
- Ron Swain Map Collection4
- Rose Hill Plantation Time Books, 18781
- Russell Maxey Photograph Collection7
- Sabina E. Wells Photographs1
- Sanborn Fire Insurance Maps of South Carolina10
- Scenes in Charleston, Georgetown, and Flat Rock, Late 19th Century12
- Senator Burnet R. Maybank Papers, 1914-19735