Collection
- South Carolina and the Civil War1
- South Carolina in Postcards2
- South Caroliniana Library Map Collection2
- Spartanburg Regional Healthcare System Collection1
- Specimens from the Bob Campbell Geology Museum1
- St. Mark United Methodist Church2
- St. Paul's Episcopal Church records, 1819-19711
- Strom Thurmond Collection, Mss 1003
- Taylors1
- The American Revolution in South Carolina7
- The Charleston Oral History Program9
- The Development of the Printed Page: 150 Examples of Handpress Printing and its Antecedents, ca. 1200 to 19374
- The Joseph Mordecai Hirschmann Collection1
- The Lucille Hasell Culp Collection2
- The Marian Bruce Logan Collection of Civil Rights Activism, Personal Correspondence, 1945-198933
- The South Carolina & West Indian Exposition Photo Passbook, 1901 - 19022
- The State Newspaper Photograph Archive303
- The WPA Week in National Defense1
- Tom Crosby oral history collection, 2006-20111
- Travels of Robert Tucker1