- San Miguel Island, Azores, Portugal1
- Savodinski Mine, Russia, Siberia1
- Saxony, Germany4
- Schaffhausen, Bavaria, Germany1
- Schneeburg, Saxony, Germany1
- Schoharie, Schoharie County, New York, United States4
- Schooley's Mountain, Morris County, New Jersey, United States1
- Schuykill River, Pennsylvania, United States1
- Schuylkill River, Philadelphia, Philadelphia County, Pennsylvania, United States2
- Scotch Plains, Union County, New Jersey2
- See Note1
- Shawneetown, Gallatin County, Illinois, United States1
- Shelby, Shelby County, Alabama, United States1
- Siciliy, Italy2
- Sicily, Italy1
- Solfatara, Napoli, Campania, Italy1
- Somerset, England, United Kingdom1
- Somerset, Windham County, Vermont, United States1
- South Carolina, United States9
- South Mountain, Lehigh County, Pennsylvania, United States1