- Covenanters--South Carolina--Chester1
- Covered bridges--South Carolina1
- Crow hunting--South Carolina1
- Cucumbers--breeding1
- Cunningham, Ann Pamela, 1816-18751
- Cyclists1
- Cypress Gardens (Charleston, S.C.)1
- Dalí, Salvador, 1904-19891
- Daniel Construction Company (Greenville, S.C.)1
- Darlington International Raceway1
- Daughters of the American Revolution1
- Dean Hall Plantation1
- Deering-Milliken Research Corp. (Spartanburg, S.C.)1
- Dental schools--South Carolina--Charleston1
- DesChamps, Minnie, 1907-19861
- Deveaux Bank (S.C.)1
- Dialectology1
- Dock Street Theatre (Charleston, S.C.)1
- Dogs--Breeding--South Carolina1
- Dogwoods1