- Edgefield First Baptist Church (Edgefield County, S.C.)2
- El Bethel Baptist Church (Cherokee County, S.C.)1
- Elim Baptist Church (Florence County, S.C.)1
- Elixirs1
- Elizabeth Baptist Church (Chesterfield County, S.C.)1
- Embarkation (Military science)1
- Enon Baptist Church (Pickens County, S.C.)1
- Enslaved persons2
- Episcopal Church--South Carolina1
- Episcopal Church. Diocese of South Carolina1
- Eugenie (steamship)2
- Euhaw Baptist Church (Jasper County, S.C.)1
- Evacuation of civilians1
- Fairview Baptist Church (Spartanburg County, S.C.)1
- Fairview Baptist Church (Union County, S.C.)1
- Fire fighters--1860-18702
- First Baptist Church (Aiken County, S.C.)2
- First Baptist Church (Charleston County, S.C.)2
- First Baptist Church (Greenville County, S.C.)1
- Fishes1