- Sigma Alpha Epsilon1
- Signs and signage--South Carolina--Moncks Corner-- 1950-1960--photographs1
- Simbeth Motel (Columbia, S.C.)1
- Simms, William Gilmore, 1806-1870 -- Correspondence1
- Smithy, Horace Gilbert, 1914-19481
- Soldiers' homes--South Carolina--Columbia1
- South Carolina Electric & Gas Company1
- South Carolina, Georgetown County, Pawleys Island1
- South Carolina--Maps1
- South Carolina--Social conditions1
- Southern Bleachery (Taylors, S.C.)1
- Spartanburg (S.C.) -- Directories1
- Spartanburg County (S.C.)--Maps.1
- Spartanburg General Hospital (Spartanburg, S.C.)1
- Spectators1
- Sports publishing1
- St. Mark United Methodist Church (Sans Souci, S.C.)1
- St. Paul's Episcopal Church (Pendleton, S.C.)1
- Statues1
- Storefronts--South Carolina--Columbia1