- Seaboard Coast Line Railroad--Pictorial works1
- Seabrook, W. E.--Correspondence1
- Silver1
- Sitton, J. J.--Correspondence1
- Slave records1
- Slavery--South Carolina1
- Sloan, J. C.1
- Smithy, Horace Gilbert, 1914-19481
- Social values--Southern States1
- Socialized medicine1
- Societies, Medical1
- Soil surveys--South Carolina--Anderson County--Maps1
- South Carolina Medical Association1
- South Carolina publications--Charleston--News and Courier, 1883.1
- South Carolina publications--Columbia--Bostick & Thornley, 19381
- South Carolina publications--Columbia--State Co., 1912.1
- South Carolina publications--Greenville--Map Shop, 19961
- South Carolina--Anderson County--Maps1
- South Carolina--Government--Planning1
- South Carolina--History--Civil War, 1861-1865--Personal narratives.1