- Rivers, L. Mendel (Lucius Mendel), 1905-19701
- Russell, Donald Stuart, 1906-19981
- School administrators1
- Seaboard Air Line Railroad Company1
- Seibels, John Jacob, 1871-19611
- Signs and signboards1
- Sligh, Strother Swift, 1900-19711
- Softball players1
- South Carolina Gamecocks (Football team)1
- South Carolina Penitentiary1
- South Carolina. Air National Guard1
- South Carolina. State Highway Department1
- Southern Bell Telephone and Telegraph Company1
- Stevens, Harold A., 1907-19901
- Strikes and lockouts--Telephone companies1
- Talmadge, Herman E. (Herman Eugene), 1913-20021
- Teachers1
- Thurmond, Strom, 1902-20031
- Timmerman, George Bell, 1881-19661
- Township Auditorium (Columbia, S.C.)1