- Railroads--South Carolina--Columbia.1
- Railroads--South Carolina--Maps1
- Railroads--South Carolina--Maps.1
- Randall, James R.1
- Reconstruction (U.S. history, 1865-1877)--Louisiana<br>United States--History--Civil War, 1861-1865--South Carolina--Columbia<br>sheet music1
- Reynolds, William, 1815-1879--Pictorial works.1
- Rhett, Alfred Moore, 1829-1889--Portraits.1
- Richardson, A. H. G.1
- Ripley, Roswell Sabine, 1823-1887--Portraits.1
- Rivers--South Carolina--Columbia.1
- Roefs, Benedict1
- Sailors--United States--Correspondence.1
- Saluda Factory (Lexington County, S.C.)1
- Sam A. Cooley (Beaufort, S.C.) (Firm)--Records and correspondence.1
- Saxton, Rufus, 1824-1908.1
- Seibels, Edwin G. (Edwin Granville), 1866-1954.1
- Semmes, Raphael, 1809-1877--Portraits.1
- Sherman, William T. (William Tecumseh Sherman), 1820-1891<br>Savannah (Ga.)--Social conditions--19th century<br>United States--History--Civil War, 1861-1865--South Carolina--Columbia<br>sheet music1
- Shuler, Joseph Linn, b. 1846--Correspondence.1
- Smallpox--South Carolina--Columbia.1