- Drayton Baptist (Spartanburg County, S.C.)1
- Drayton Methodist (Spartanburg County, S.C.)1
- Drayton family1
- Drayton, Glenn, 1788-18141
- Druen, J. V.1
- Duckett, Arthur C.1
- Due West Associate Reformed Presbyterian Church (Due West, S.C.)1
- Due West Baptist Church (Due West, S.C.)1
- Duncan (Spartanburg County, S.C.)1
- Duncan Memorial (Spartanburg County, S.C.)1
- Durant, Marion Ashton1
- Durant, Moriah Ashton1
- Ebenezer Methodist Episcopal Church (Abbeville County, S.C)1
- Edwards, Coley1
- Edwards, James S.1
- Eirvin Chapel (Spartanburg County, S.C.)1
- Ellis, C. M.1
- Emma Grey Memorial (Spartanburg County, S.C.)1
- Engleside (Spartanburg County, S.C.)1
- Epiphany Mission (Spartanburg, S.C.)1