- Spence, Floyd D., 1928-20011
- St. Matthew's Lutheran Church (Charleston, S.C.)1
- St. Philip's Church (Charleston, S.C.)1
- Star of the West (Steamship)1
- Steam power plants1
- Street-railroads1
- Streetlights1
- Streets--South Carolina1
- Summerall, Charles Pelot, 1867-19551
- Sumter National Forest (S.C.)1
- Sumter, Nathalie deLage, 1782-18411
- Sundials1
- Swine--Housing1
- Tamassee DAR School (Tamassee, S.C.)1
- Taverns (Inns)1
- Television journalists1
- Texaco, Inc.1
- Textile factories1
- Thornhill, Theodore Wilbur, 1892-19781
- Tillman, Benjamin R. (Benjamin Ryan), 1847-19181