- Ruckstull, F. W. (Fred Wellington), 1853-19429
- Russell, Donald Stuart,1906-19981
- Saint Francis de Sales Catholic Church (Columbia, S.C.)1
- Sanatoriums--South Carolina--Columbia1
- Sanatoriums--South Carolina--State Park1
- Schools--South Carolina--Columbia11
- Seaboard Air Line Railway Company1
- Security Federal Savings and Loan Association1
- Sesquicentennial State Park (Columbia, S.C.)1
- Shandon Methodist Church (Columbia, S.C.)1
- Shandon Presbyterian Church (Columbia, S.C.)1
- Sheild's Foundry (Columbia, S.C.)1
- Simbeth Motel (Columbia, S.C.)1
- Simkins, Modjeska Monteith, 1899-19221
- Simkins, Modjeska, 1899-199289
- Skyscrapers--South Carolina--Columbia1
- Skyscrappers--South Carolina--Columbia1
- Smith, H.I.1
- Soldiers' homes--South Carolina--Columbia3
- South Carolina9